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From ASCO Post Staff
Posted: 2023/01/24 12:12:00 PM
Last update:
Many people considering screening for colorectal cancer may need information about their own risk when making screening decisions. Researchers evaluated five online colorectal cancer risk calculators to determine their availability, ease of use, risk prediction capabilities, and “behind the scenes” quality, how each was developed, and whether it is based on rigorous statistical evidence. These findings were published by Marat and Imperiale. American Journal of Medicine.
Analysis details
To compare the risk calculators, investigators reviewed public data on the tools (sometimes none were found) and created hypothetical test scenarios.
The researchers noted that all online risk calculators required individuals to enter their age, gender, body mass index, smoking, and family history of colorectal cancer. Queries on race, ethnicity, education level, history of diabetes, history of colonic polyps, dietary habits, medications, and physical activity were not consistently included.
They found that there are varying amounts of evidence supporting different risk assessment tools. However, there was fairly close agreement among risk calculators for the short-term risk of colorectal cancer (5 years, possibly 10 years). Lifetime risk predictions were inconsistent.
Overall, the researchers found the National Institutes of Health’s National Cancer Institute (NCI) risk assessment tool to be the most reliable online risk calculator for colorectal cancer.
Conclusion
“We conducted this study to help the public and clinicians recognize the ease of use of these risk assessment tools and to provide guidance on how to decide which to use.” explained the study authors. Jennifer K. Marratt, MD, MS, Assistant Professor of Medicine, Department of Gastroenterology and Hepatology, Indiana University School of Medicine. Dr. Maratt said NCI’s risk calculator was developed and validated in a US patient population, so it may be the best risk calculator available to individuals living in the US (compared to other risk calculators). when compared). “In addition, risk prediction tools such as the NCI Risk Calculator could be linked and integrated into a patient’s electronic health record. can do. [of colorectal cancer]tobacco use, diet, exercise, and other lifestyle factors influence risk when discussing colorectal cancer screening with patients,” she emphasized.
“I was surprised to find that some risk calculators had no evidence, [were] We are pleased to announce that NCI’s Colorectal Cancer Risk Assessment Tool has been validated. “People’s behavior can change over time, so we weren’t surprised that calculators had more difficulty estimating long-term risk,” the study authors stressed. Thomas F. Imperiale, M.D.Lawrence Lumen Professor of Gastroenterology and Hepatology, Indiana University School of Medicine, and Professor of Medicine, Department of Hematology/Oncology, Indiana University School of Medicine, Adjunct Professor, Indiana University School of Public Health-Bloomington, and Margaret Mary Medical Director of Health. “Patients can choose to continue with certain lifestyle choices, discontinue them, or make new ones. Of course, they can choose to be screened or, unfortunately, not to be screened.” You can,” he concluded.
NCI’s Colorectal Cancer Online Risk Assessment Tool can be found at ccrisktool.cancer.gov.
Disclosure: For full study author disclosures, visit amjmed.com.
The content of this post has not been reviewed by the American Society of Clinical Oncology (ASCO®) and does not necessarily reflect the views or opinions of ASCO®.
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